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Common reasons include: Unexpected side effects like fatigue, breakouts, or digestive issues No visible change even after consistent use The need to combine drops with sun exposure or other products The high cost of maintenance over time Others say they felt misled by influencer endorsements and assumed the product was approved or tested, only to discover later that most brands are unregulated and unsupported by clinical trials

At the time of first assessment, all probands described fulfilled clinical criteria for cEDS, which included three different classification criteria dependent on the year that they were assessed (Table 1) (Berlin, 22 Villefranche, and 2017 New York criteria)

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Deconstructing the Gastrointestinal Repair Mechanisms While BPC-157 exhibits systemic protective effects, its most extensively studied applications are within the gastrointestinal (GI) tract