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In addition, it is noteworthy that several foundational studies have reported alterations in microglial gene expression, plausibly reflecting DAM-like phenotypes, in both aging and AD models of mice and humans (Colangelo et al., 2002

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Previous studies have linked ENOC to endometriosis, suggesting that reduced GLP-1 levels in peritoneal fluid may contribute to endometriosis development 75,76,77