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Function: Semaglutide increases insulin secretion, lowers glucagon levels, slows gastric emptying, and reduces appetite, contributing to both improved glycemic control and weight loss
The SUSTAIN-6 trial, a landmark study, revealed that semaglutide significantly reduced the risk of major adverse cardiovascular events, including heart attack, stroke, and cardiovascular death, compared to placebo
The combination may produce faster noticeable appetite changes, but it also comes with additional side effect potential
eLife, 14, e12270663
At this point: The amount of medication you take in with each dose equals the amount your body clears
While tirzepatide shows superior weight loss in head-to-head trials, semaglutide offers proven cardiovascular benefits and multiple formulation options
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