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Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo

Photo by Innerbody Research Around 30-50% of American adults dont get enough sleep.1 The consequences of this insufficiency can be steep, as without a regular 7-8 hours rest per night, a person can find themselves at risk for depression, decreased cognitive function, and an increased risk of cardiovascular and endocrine dysfunction.2 For the many millions of people with sleep deficiency, a peptide called DSIP could be a solution, although some researchers might disagree

Considerations for the Design and Reporting of Enzyme Assays in High-Throughput Screening Applications

With such a potent solution, even a slight miscalculation or drawing up a little too much can result in a much higher dose than intended

Advanced quantitative proteomic techniques, such as tandem mass tag-based proteomics, have identified proteins enriched in CSC populations, particularly those involved in oxidative stress adaptation, extracellular matrix remodeling, and EMT, which facilitate metastatic potential and therapy evasion

Another relevant contribution came out of a collaboration by researchers at the University of Washington, Washington State University, and the Bastyr University Research Institute