When levels drop below 130 mEq/L, symptoms appear
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Kidney function can improve modestly with weight loss as well
I emailed during off-hours and received confirmation first thing the next morning
These typically occur early in treatment and resolve within the first few weeks
Other Names for This Condition 5-oxoprolinemia 5-oxoprolinuria Deficiency of glutathione synthase Deficiency of glutathione synthetase Pyroglutamic acidemia Pyroglutamic aciduria Additional Information & Resources Genetic and Rare Diseases Information Center Patient Support and Advocacy Resources Clinical Trials Catalog of Genes and Diseases from OMIM Scientific Articles on PubMed References Al-Jishi E, Meyer BF, Rashed MS, Al-Essa M, Al-Hamed MH, Sakati N, Sanjad S, Ozand PT, Kambouris M