Symptoms of vitamin D toxicity are due to increased calcium levels in the blood and can include nausea, vomiting, muscle weakness, neurologic or psychiatric symptoms, pain, loss of appetite, dehydration, increased urination, excessive thirst, and kidney stones
During these sensitive phases, the substances protective properties can influence the effectiveness of treatments or biological processes
In summary, we have identified hepatocyte-derived Dpp4 as a key factor in regulating the bioactivity of GLP-1 in the PV and extended these findings to demonstrate that its elimination results in a reduction in HGP
Although these findings may a priori not be applicable for a proper exposure assessment in other countries, it seems plausible to estimate that normal daily intake rates via Western-style diets (not by enriched products) may not exceed 200 mg/d
Published December 19, 2024
Clinical judgment and research rigor will be critical in translating these molecular insights into standardized care
