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At the 12-week mark, average weight loss across all dose groups reached 8.7%

MORs are well-established as the main regulators of gastrointestinal motility and secretion and have been shown to mediate opioid-induced constipation 10,21,22

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Aunque actualmente se encuentra catalogado principalmente como compuesto de investigacin, el inters cientfico y clnico contina aumentando gracias a los resultados observados en estudios preclnicos y experiencias reportadas en protocolos experimentales