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The reviewed publications included mechanistic studies, clinical trials and systematic reviews involving human subjects that report relevant findings on direct epigenetic evidence (such as DNA methylation levels), biochemical markers or clinical outcomes associated with disease activity and therapeutic response

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doi: 10.1093/bioinformatics/btv693

Clinical studies have confirmed significant alterations in both the gut microbiota composition and BAs profiles in SZ patients (77), highlighting a potential correlation between BAs dysregulation and the disorder

This interview has been lightly edited and condensed for clarity and length

CagriSema is highly effective, but tirzepatide (Zepbound) edges it out in a direct comparison