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GLP-1 treatment was associated with clinically meaningful weight loss at 24 weeks post-initiation, with a mean weight loss of 13.9% (tirzepatide 14.9%, semaglutide 10.9%)

A retrospective cohort study to investigate the distinct effects of antihypertensives on depression enrolled 181,709 patients and found that other antihypertensives may have a negative effect on the risk of depression compared with ARBs (216)

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