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[1] Understanding these foundational mechanisms helps contextualize questions about whether the body develops tolerance to tirzepatide's effects over extended periods of use

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CT-388 would be the only branded dual GLP-1R/GIPR agonist with full exclusivity after tirzepatide faces generic competition in the 2036 to 2041 window

doi: 10.1002/psp4.13014 25 CatandiGDChengMHChiccoAJChenTCarnevaleEM