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PMC 434288

Guerrero-Romero F, et al

11 Conclusion Periodontitis is far more than a localized oral condition, it is a silent, modifiable and clinically actionable driver of systemic inflammation

In trials with semaglutide was added on to insulin with or without metformin, severe hypoglycemia was reported in 1% of patients receiving the 14 mg tablets, 1% of patients receiving placebo, and 0% of the patients receiving the 7 mg tablets

Specifically, null variants of the GSTM1 and GSTT1 alleles contain large deletions, and individuals who inherit two copies of the GSTM1 -null or GSTT1 -null alleles cannot produce the corresponding GST enzymes (54)

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