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Following repeated oral exposure for 4 weeks (1.75, 7, 28 mg/kg/day), granulomatous inflammation was observed, characterised by infiltration of macrophages and occasional lymphocytes into terminal bronchioles and alveolar spaces

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The anti-ferroptotic properties of BH 4 mainly involve its ability to function as a powerful antioxidant and to mediate CoQ 10 synthesis

doi: 10.1093/brain/awad010 Summary Keywords autism, pathophysiology, bioenergetics, subtypes, biomarker, metabolomic, stratification, mitochondria Citation Smith AM, Donley ELR, Ney DM, Amaral DG, Burrier RE and Natowicz MR (2023) Metabolomic biomarkers in autism: identification of complex dysregulations of cellular bioenergetics

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