A 2015 systematic review and meta-analysis of 8 randomised trials found that NAC produced higher pregnancy rates than placebo across the placebo-comparison subgroup (pregnancy odds ratio 3.97, 95% CI 2.077.59), though in the same analysis NAC was less effective than metformin for pregnancy outcomes (OR 0.40, 95% CI 0.230.71)
This is medically normal and does not indicate treatment failure
The injection site does not directly affect reflux, but subcutaneous injections in the abdomen versus the thigh can produce slightly different absorption rates, which might indirectly influence the timing of GI effects
Related reading: Atkins Diet, Low-Carb Diet, Mediterranean Diet, Glycemic Index, Protein and Weight Loss on GLP-1 Medications, and Why Muscle Preservation Matters on GLP-1s.
Contact Quality Care Internal Medicine & Medspa in Allen, TX, to schedule your weight loss consultation.
In case if any serious risk emerges, the licence can be modified or withdrawn