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Macrophage activation and foam cell formation may explain the elevated CRP serum levels and contribute to disease progression (Figure 9)

2) direct modulation of cell proliferation and apoptosis

Thompson is chair of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Panel on Management of Immunotherapy-Related Toxicity as well as co-chair of the expert panel that developed the ASCO guideline

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