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GIP contributes to islet trihormonal abnorMalities in type 2 diabetes

Deng, H

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Options may include switching to a different GLP-1 medication, adjusting the dose, or developing a plan to support weight maintenance through nutrition and behavioral strategies during the gap

The primary mechanism of action involves enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated

For example, a major trial published in The New England Journal of Medicine reported greater average weight loss among participants receiving semaglutide compared with placebo