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In contrast, the long-term use of artificial cyanocobalamin supplements does not have a direct biological effect and must first be converted in the body into one of the three natural forms of B12

Liver findings included lower liver weight, reduced triglyceride content and less severe histological features of steatosis and inflammatory-cell infiltration in treated mice

It functions by inhibiting the NNMT enzyme, which may contribute to increased cellular NAD levels, a key factor associated with improved metabolism and body composition outcomes

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