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PPS is the only FDA-approved oral agent for the treatment of IC/BPS and is by far the most-studied oral medication in use for IC/BPS

95% CI, 0.23 to 5.53

Interleukin 6 (IL-6) is a cytokine that plays a key role in regulating inflammation, immune response, acute phase response, and hematopoiesis, and IL-6 content is closely related to the degree of inflammatory response

Muscle damage induces the expression of the IGF-I isoform mechano growth factor (known as MGF, see glossary) followed by that of the calcium-dependent cell adhesion molecule and marker of satellite cells M-cadherin

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The multifaceted therapeutic role of N-acetylcysteine (NAC) in disorders characterized by oxidative stress