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Multiple studies have reported that Epithalon administration can extend both mean and maximum lifespan by 10-25% or more compared to control animals - effects approaching those seen with caloric restriction

Circadian gene expression and BMAL1 acetylation are disturbed in liver-specific SIRT1 mutant mice (Nakahata et al., 2008)

They help boost energy, support metabolism, and improve mood, all of which can contribute to better weight management

If serum B12 levels are persistently low, consider alternative therapy (e.g., intramuscular or subcutaneous vitamin B12 therapy)

Avoid intense or repeated use of the injected muscle for at least 24 hours

Disclosure of interest: None