In addition to their weight loss benefits, these drugs also act through gut-brain signaling and central nervous system pathways involved in appetite, reward, and feeding behavior, although the extent to which individual agents cross the blood-brain barrier remains an active area of investigation
Semaglutide reduces body weight by around 14% on average, while tirzepatide in clinical trials has shown up to 20% weight loss on average
Hearing, vision, and sensory input Hearing and vision are now central to the dementia-prevention conversation
Call your healthcare provider right away if you experience serious side effects, such as severe stomach pain, chest pain, new or worsening headaches, blurred vision, fever, severe hypoglycemia, or dehydration after starting a GLP-1 or birth control
GLP-1 medications are typically prescribed for individuals who have a body mass index (BMI) of 30 or higher, or for those with a BMI of 27 or higher who also have at least one weight-related health condition, such as type 2 diabetes or high blood pressure
Ethics declarations Ethics approval and consent to participate The study was approved by the ethics committee of the Medical University Vienna (ethical approval number: 2216/2020)