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13,14 This study sup- ports the conclusions of the European Medicines Agen- cys investigation and the US Food and Drug Admin- istrations preliminary evaluation 32 that the available evidence does not support a causal association between use of GLP-1 receptor agonists and suicidal and self-injurious thoughts and actions

Note: the effects are mild to modest as compared to injectables & topical retinoids

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Key Risk: Regulatory/payer pushback (pricing controls, pharmacy benefit restrictions, or clinical liability) prevents Amazon from capturing durable economics from GLP-1 delivery