To begin with, GLP-1 is secreted by L cells in the lower intestine, and its secretory stimuli include nutrients, the gut microbiota itself, and metabolites of the gut microbiota, such as short-chain fatty acids 47,48
And that's because when we're losing weight, our bones undergo a little less stress
While the research base for microdosing, specifically, is still developing, and lower-dose protocols are being explored, though clinical evidence for efficacy at sub-therapeutic doses remains limited
Specialty medications are subject to distribution restrictions that don't apply to standard drugs
Dolinsky VW, Morton JS, Oka T, Robillard-Frayne I, Bagdan M, Lopaschuk GD, et al
A fraction of that, sometimes one-tenth, targeted at the inflammatory machinery that drives autoimmune disease from the inside out