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Some patients are happy with their progress but still want help with: That does not necessarily mean GLP-1 treatment failed

It may be important to consider the role of dopaminergic signaling in feeding behavior in the context of GLP-1, as individuals with obesity have been found to have decreased D2R expression in striatal regions that project to the LH, suggesting that obesity may lead to decreased satiability and increased hyperphagia through this circuit [128]

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Glickman says

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