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Strikingly, estrogen deprivation was shown to be the principal mediator of impaired wound healing in the elderly population when a microarray study revealed that 78% of genes differentially expressed between wounds from young and aged men were estrogen-regulated, while only 3% were related to intrinsic aging (Thornton, 2013)

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Those on Certain Medications : Some medications, such as metformin (for diabetes) or proton pump inhibitors (for acid reflux), can interfere with B12 absorption

doi: 10.3109/01913123.2011.627491

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