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Therefore, more clinical trials utilizing a large generalizable T2DM patient population with less influence from baseline characteristics and longer follow-up durations are needed to help guide clinical decision-making and reduce the burden of T2DM while also promoting cardiovascular health

Long-Term Heart Health and GLP-1s Interestingly, while some people worry about chest pain as a side effect, the long-term data on semaglutide actually points toward cardiovascular benefits

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This action suppresses hepatic glucose production and influences insulin sensitivity through activation of the PI3K-Akt-FoxO1 signaling cascade [17]