This stimulation can lead to undesirable side effects such as insomnia, anxiety, and cardiovascular issues, including elevated heart rate and blood pressure
Diabetes Res Clin Pract 170:108532
Several retrospective studies associated the drug class with lower glaucoma risk and reduced ocular hypertension incidence, while preclinical work demonstrated reduced retinal ganglion cell loss and optic nerve damage in experimental models. The experimental literature also points to inflammatory modulation, oxidative stress reduction and retinal ganglion cell survival pathways as possible mechanisms. Smaller studies evaluating IIH and DED reported reductions in intracranial pressure and improved ocular surface parameters, respectively, among treated patients. READ MORE: Blinding Disease-Weight Loss Drug Link: EMA Announces Start of Semaglutide Investigation The evidence base still has limits The review flagged recurring methodological constraints across the literature: reliance on retrospective EHR analyses and ICD-based coding, heterogeneous ocular endpoints, inconsistent imaging and limited longitudinal follow-up

For many patients, this results in: significant weight reduction improved insulin sensitivity better metabolic health reduced appetite and cravings Because of this mechanism, Mounjaro is often considered one of the most effective medical weight loss treatments currently available , alongside other GLP-1 medications such as Ozempic, Wegovy, and Saxenda
Avoid Compounded Mounjaro or Zepbound Avoid compounded (custom-mixed) tirzepatide from compounding pharmacies
Musty or metallic odor : Thinning tissue and less natural lubrication can cause irritation or light bleeding, which sometimes creates a metallic smell