Emerging evidence highlights the gastrointestinal tracts crucial role in systemic metabolism, with procedures like RYGB demonstrating enhanced glucose metabolism and reduced medication dependence shortly after surgery [4, 13,14,15]
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The fact that current treatments either manage symptoms without addressing pathology or remove damaged veins without preventing new ones means there's real value in investigating whether peptide-based repair mechanisms could change that
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Kenchaiah S, Evans JC, Levy D et al (2002) Obesity and the risk of heart failure