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Virtual And Physical Prototyping, 19 , Article e2400329
John, G
10.1111/nyas.13145 144
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To test whether an IH-dependent pro-oxidant state played a role in suppressing adult neurogenesis during the second critical period, we administered MnTMPyP concurrent with IH LATE in mice hemizygous for HIF-1a among birth-dated INPs
Abbreviations ASL: Airway surface liquid ALI: Airliquid interface COPD: Chronic obstructive pulmonary disease WHO: World health Organization PM: Particulate Matter AED: Aerodynamic equivalent diameter ROS: Reactive oxygen species RNS: Reactive nitrogen species NAC: N-acetylcysteine hNEC: Human nasal epithelial cell poly I:C: Polyinosinic:polycytidylic acid HDM: House dust mite BaP: Benzo[a]pyrene CYP27B1: 1-Hydroxylase RSV: Respiratory syncytial virus hBEC: Human bronchial epithelial cell LPS: Lipopolysaccharide BALF: Bronchoalveolar lavage fluid TH17: T helper 17 DEP: Diesel exhaust particle EMT: Epithelial-mesenchymal transition CSE: Cigarette smoke extract GSH/GSSG: Glutathione (reduced/oxidized) CF: Cystic fibrosis IPF: Idiopathic pulmonary fibrosis References Yang W
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