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Most metabolism associated with the cytochrome P-450 superfamily takes place in the liver but these enzymes are also present in the epithelium of the small intestine

10.1021/acs.jproteome.5b00144 Pubmed Abstract CrossRef Google Scholar View reference in article 34

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pH sensitivity

Conditions such as low stomach acid, dysbiosis, and leaky gut not only compromise the skin but may also lead to future health problems, including autoimmune diseases, food sensitivities, allergies, asthma, depression, and even cancer

A surgeon would then snip off the ends to expose and connect the healthier tissue