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Trimethylamine -N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice

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& Kivimki, M

Funding This work was supported by Sichuan Province Foundation (2021NZZJ0016), Fok Ying Tung Education Foundation (171019), and the 111 project (D17015)

DPP-IV modulates diverse cellular processes including survival, proliferation, and differentiation, and thereby enhances or diminishes tumorigenesis depending on the types or phases of tumors (Havre et al., 2008)

Avoid repeated freeze-thaw cycles, which degrade peptide structural integrity