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Data was analyzed using the independent t test

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Simultaneously, circRNA also plays a role in drug resistance through competitive miRNA binding, altering target gene expression and consequently affecting drug resistance (88)

Generation of HeLa cells stably expressing APEX2 For generation of stable cell lines, the pLPCX retroviral expression vector encoding APEX2-GFP or mito-APEX2 (Su9-APEX2) was transfected into the packaging cell line Phoenix-AMPHO

glial cell line derived neurotrophic factor GDNF the growth factor was delivered by cannula to the putamen as the naked protein or as an AAV2 carrying c-DNA construct

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells