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In addition, there is an increase in lymphocyte differentiation in the direction of Th 22 and Th 17, leading to the production of Il-22 and Il-17, respectively

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Furthermore, transcriptomics performed from TMX2 deleted PR 20 and GR 20 expressing neurons revealed upregulation of pro-survival unfolded protein response (UPR) pathway genes and downregulation of calcium-binding and apoptotic genes