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Data from PIONEER 1 were not included because oral semaglutide was given as monotherapy [12], PIONEER 2 was excluded because all patients randomised to oral semaglutide or comparator were receiving background metformin (and no other background glucose-lowering medication) [13], and PIONEER 6 was excluded because it was a cardiovascular outcomes trial [14]

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Hernn MA, Robins JM

PubMed Tjokroprawiro A, Murtiwi S, Tjandrawinata RR

The efficacy and safety of this formulation are well demonstrated in clinical application (101)

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Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13 , 30753087