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In general, ECs are connected side-by-side through transmembrane adhesion proteins [37], including vascular endothelial and neural cadherin at adherent junctions [38, 39], occludin [40], and members of the claudin family [41], as well as the junctional adhesion molecule (JAM) family at tight junctions [42]

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NAC serves as a crucial building block for glutathione, one of the bodys most important antioxidants

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To address the critical issue of BBB permeability, studies using [H]Dihexa and [C]inulin in rats revealed that Dihexa avidly concentrated in all examined brain regions including the prefrontal cortex, hippocampus, hypothalamus, striatum, thalamus, midbrain, brain stem, and cerebellum, compared to blood