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Its detected by: - Increased serum creatinine (always compare with baseline creatinine!) - Decreased urine output Causes of AKI Pre-renal (most common): Inadequate perfusion - Kidneys are intact but starved of blood Causes: dehydration, blood loss, sepsis, heart failure Intrarenal: Direct damage to kidney tissue - can occur after prolonged pre-renal AKI Causes: Nephrotoxic medications (e.g

Neuroscience 64 : 619928 Foreman PJ, Perez-Polo JR, Angelucci L, Ramacci MT, Taglialatela G

[00:31:36] Emily Field: You do not have to interpret every sign of stronger appetite suppression as a positive

How to Choose Between Them You cant go wrong with either but your choice depends on what you want to prioritize: surface rejuvenation or deep repair

Harrison DE, Strong R, Allison DB, Ames BN, Astle CM, Atamna H, et al

For instance, p300/CBP-mediated lactylation of HMGB1 concurrently inhibits deacetylase Sirt1 activity and enhances HMGB1 acetylation