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Mol Pharmacol (2014) 85(5):77788

You want progress to feel personal and encouraging, not like a score or ranking compared with other people

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Validating these findings, we show that deletion of the mitochondrial pyruvate carrier, which is known to decrease TCA cycle activity and protect the liver from diet-induced injury, also diminished NADPH, elevated glutathione oxidation, and alleviated ER stress