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Among these changes, the KEGG pathway analysis showed that genes involved in the fatty acid beta-oxidation (for example, Acadm , Hadh, and Ehhadh ) and carnitine synthesis (for example, Bbox1 ) were down-regulated in SLC25A45 KO mice relative to control mice, whereas the glycolysis (for example, Hk2 , Gapgh , Pfkfb3 ) and mitochondrial OXPHOS pathways (for example, Ndufa3, Cox7a2, Cpt1a ) were upregulated in SLC25A45 KO mice ( Fig

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