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Availability of Data and Material Not applicable Ethics Approval Not applicable Consent to Participate Not applicable Consent for Publication Not applicable Author Contributions All authors (F.P, S.M.O, J.M, F.C.S) meet ICMJE authorship criteria, made substantial contributions to the conception and design of the work and to drafting or critically revising the manuscript, approved the final version, and agree to be accountable for all aspects of the work

Grouping and drug or placebo administration were done by one of the nurses, and other team members were unaware

The time it takes to feel better after IV hydration can change based on the individuals condition and the seriousness of their dehydration

Thermoresponsive gels containing AuNPs were synthesized using Pluronic 127 alone (F1) and with hydroxypropyl methylcellulose (F2) and are considered smart intelligent nanosystems as they perform dual-action such as antibacterial and wound healing effect

Glutathione Antioxidant that lightens and evens skin tone