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Indeed, thyroid dysfunction is the most frequent endocrine irAE and may affect up to 40% of patients receiving ICIs (Baraka et al

Common contraindications cited in the research-use community include: anyone with active or recent cancer (BPC-157 and TB-500 promote angiogenesis), people with Wilson's disease or other copper-metabolism disorders (GHK-Cu component), anyone pregnant or breastfeeding (no safety data), and athletes subject to WADA testing (BPC-157 and TB-500 are prohibited)

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And where did this substance even come from

It doesn't suppress natural hormone production or cause dependency