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These tradeoffs are not merely theoretical: in the pilot phase of the PRECIDENTD pragmatic trial, participants assigned to dual therapy had substantially lower medication fill rates and higher discontinuation than those on monotherapy, driven largely by side effects, cost, and access [36]

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Storing and Handling Your Semaglutide Oral Medication To maintain its effectiveness, keep your oral semaglutide in the refrigerator when not in use

32 CooperO.SeoH.AndrabiS.Guardia-LaguartaC.GraziottoJ.SundbergM.et al (2012)

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