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The primary evidence regarding tirzepatide's cancer risk comes from the SURPASS clinical trial program for type 2 diabetes and the SURMOUNT trials for weight management

Food supplements must not be used as a substitute for a balanced and varied diet

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For patients that are not good candidates for surgery due to age or extensive medical history, lifestyle modifications are important to alleviate some of the symptoms

For instance, SNPs like rs3131621, rs9275596, and rs11244 in the HLA region are associated with increased primary sclerosing cholangitis (PSC) risk and are crucial in distinguishing patients with UC-PSC from patients with UC alone [27]

Effects of GLP-1 and its analogs on gastric physiology in diabetes management