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Lower blood sugar, improved cholesterol, or reduced HbA1c levels (checked every 36 months) are all signs of progress

For common thyroid conditions like hypothyroidism or Hashimoto's, GLP-1 medications are not contraindicated

ESC Heart Fail 7:34383451 Vilsbll T, Christensen M, Junker AE, Knop FK, Gluud LL (2012) Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomized controlled trials

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This matters even more if you also take blood pressure medications

Yang L, Yatomi Y, Miura Y, Satoh K, Ozaki Y