The Wall Street Journal reports that it found more than 50 sites selling what they dubiously termed pharmaceutical grade semaglutide and tirzepatide, the active ingredients on Ozempic, Wegovy, and Mounjaro
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For every extra pound a person carries, the force exerted on the lower back increases significantlysome estimates suggest up to four times the amount of pressure during activities like walking or climbing stairs
Additionally, higher-dose semaglutide formulations (such as Wegovy 2.4 mg, licensed specifically for weight management) may be appropriate for certain patients meeting specific NICE criteria (TA875), though this requires specialist weight management services and is typically limited to a 2-year treatment duration
The authors declare no other competing interests