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The use of other chemical spacers was also explored, with the aim of substituting the optically active Glu with a simple, non-chiral spacer ( in vivo protraction without compromising receptor potency

Based on the characterization of their binding mechanisms, three distinct groups of DPP4 inhibitors have been identified: saxagliptin, alogliptin, and sitagliptin, each representing a different class

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It is frequently classified in scientific literature as a stable gastric pentadecapeptide, originally derived from a protein found in human gastric juice