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[DOI] [PubMed] [Google Scholar] 325.Tatetsu H, et al

However, this ERK5 destabilization is quantitatively and kinetically much less efficient than the targeted, proximity-induced degradation achieved by the bifunctional ERK5-CHAMP (HLE, RNK06138) with differences in DC 50 and Dmax potencies (Fig

Accordingly, the antiproliferative activity of both compounds was evaluated using the MTT assay after 72 h of treatment against the cancer cell lines A2780 and A2780cisR

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