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Common negative reports include increased injection site discomfort, slightly more GI upset (particularly during the first few weeks), and disappointment when the dramatic results promised by marketing materials do not materialize

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Genetics of Type 1 Diabetes The majority of genetic loci associated with the development of type 1 diabetes map to the human leukocyte antigen (HLA) class II proteins which are encoded for by genes in the major histocompatibility complex (MHC) which is located on chromosome 6p21