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Preserves natural feedback loops: The physiological stimulation allows for endogenous regulation without suppressing the pituitary axis

[15] In practice, hydroxocobalamin injections achieve higher and more sustained vitamin B concentrations compared to cyanocobalamin

However, these were medical-grade formulations containing an actual prescription drug, not a natural supplement

Once inside the brain, ALCAR donates its acetyl group to the enzyme choline acetyltransferase, directly driving the synthesis of acetylcholine

A few months later the drug gained authorisation in Canada, the European Union, Japan and then Australia in 2019