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However, we tried several values of V mean and V eff as well as replacing the ohmic formalism by the GHK formalism and every version of the model gave a qualitative synergy

The medication is contraindicated during pregnancy and requires prescription and clinical monitoring

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It may not be required in cases where the clinical features and antibody tests are evident, but in situations where there is uncertainty such as in the 20-30% of Sjogrens patients who do not possess autoantibodies, it may be helpful in diagnosis

The most common ones include: Nausea Vomiting Diarrhea or constipation Stomach pain Fatigue Most side effects are mild and improve over time