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Mechanistically, DAMPs can be comprehensively classified into two primary categories: endogenous alarmins, such as HSP60, HSP70, and S100 proteins, which interact with specific TLRs through welldefined molecular interactions via CD14 and/or MD2

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3 Results 3.1 Characterization of SBA-15 and SNCDs nanoparticles Functionalized SBA-15 mesoporous silica nanoparticles (MSN) were prepared using an aqueous system that consisted of tetraethyl orthosilicate (TEOS) as the silica precursor and cetyltrimethylammonium bromide (CTAB) as the surfactant, following the methodology described in reference [21]

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