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Extreme caution is advised in patients with epilepsy, advanced age, or chronic pulmonary disease because hypoxia and acidosis lower the seizure threshold and potentiate cardiotoxicity
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More frequently, the patient experiences other gastrointestinal symptoms, including gastroesophageal reflux (GERD), irritable bowels, constipation or delayed gastric emptying that causes bloating
The NCI is part of the National Institutes of Health (NIH)
An acute inflammatory response is associated with several signs including redness, swelling, pain, heat, and loss of function
This reaction forms polyprenyl-4-hydroxybenzoate (PPHB), the first committed intermediate in CoQ biosynthesis that links the aromatic ring with the hydrophobic tail
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