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Oxidative stress induces degradation of mitochondrial DNA
Annual screening for diabetic complications (retinopathy, nephropathy, neuropathy, foot problems) should continue as per NHS diabetes annual checks guidance
The most common side effects of tirzepatide are gastrointestinal, including nausea (12-29%), diarrhea (13-23%), vomiting (4-9%), constipation (6-11%), and abdominal pain
pregnancy should be avoided during treatment (effective contraception is recommended)
Osmotic laxatives like polyethylene glycol (Miralax) and magnesium citrate are considered first-line options because they work gently by drawing water into your colon, softening stool without forcing rapid bowel movements